research Signaling pathways in the mechanisms of drug action
Signaling pathways are key targets for developing effective drugs.
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research A comparative study of the effects of 4-META/MMA-TBB resin and cyanoacrylate on wound healing of skin defects
4-META resin heals skin wounds faster and better than cyanoacrylate.
research Hirsutism and virilism
Hirsutism treatments can slow new hair growth, but existing hair needs removal, and eflornithine helps reduce hair growth.
research Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed Macaques
RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.
research Pharmacology and Pharmacokinetics of Minoxidil
Minoxidil treats high blood pressure and side effects can be managed.
research Adverse effects of low-dose oral minoxidil for androgenetic alopecia in 435 patients
Low-dose oral minoxidil may cause side effects like hypertrichosis and is not suitable for everyone.
research Anti-graying effect of the extract of Pueraria thunbergiana via upregulation of cAMP/MITF-M signaling pathway
Pueraria thunbergiana extract may help prevent hair from turning gray.
research Botanical drug preparations for alleviating hair loss in menopausal women: a global ethnopharmacological mini-review
Botanical treatments like saw palmetto, rosemary oil, and ginseng may help reduce hair loss in menopausal women.
research Finasteride to treat recurrent priapism in sickle cell anemia
research Clobetasol/minoxidil
research Hyaluronic acid microneedles enhance transdermal delivery of minoxidil derivatives with 1,2,4-oxadiazole-5-one unit for effective hair regeneration: Insights from X-ray crystallography and animal models
Hyaluronic acid microneedles help deliver minoxidil derivatives effectively for hair regrowth.
research Efficacy of Pine Needle Extract in a Rat Model of Androgenic Alopecia
research Influence of Saw palmetto and Pygeum africana extracts on the urinary concentrations of endogenous anabolic steroids: Relevance to doping analysis
Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.
research Hirsutography: Photographic measurement of linear hair growth in hirsute women during comparison of anti-androgen treatments
The photographic method accurately measures hair growth and both treatments effectively reduced hair growth in hirsute women.
research LB1024 Ashwagandha (Withania somnifera) seed plant exosome-like nanovesicles promote in vitro cellular regeneration of human dermal hair follicle, endothelial and fibroblast cells
Ashwagandha seed nanovesicles may help regenerate hair and skin cells.
research A STUDY OF EFFICACY AND SAFETY OF ORAL MINOXIDIL IN MALE ANDROGENETIC ALOPECIA
Oral minoxidil effectively promotes hair growth in men with hair loss, but caution is needed for older or heart-risk patients.
research Identifying the Active Components and Mechanisms of Persicae Semen in Treating Androgenetic Alopecia: Insights from Network Pharmacology and Experimental Evaluations
Amygdalin in Persicae Semen may help treat hair loss by promoting hair growth and regulating key pathways.
research Minoxidil suppressed mitochondrial depolarization and subsequent neuronal cell death by decreasing intracellular potassium level
Minoxidil may protect the brain from damage by preventing cell death and energy loss.
research Hypaphorine, an indole-3-acetic acid antagonist delivered by the ectomycorrhizal fungus Pisolithus tinctorius , induces reorganisation of actin and the microtubule cytoskeleton in Eucalyptus globulus ssp bicostata root hairs
Hypaphorine from a fungus changes the internal structure of Eucalyptus root hairs, stopping their growth.
research A summary of in vitro, phase I, and phase II studies evaluating the mechanism of action, safety, and efficacy of clascoterone (cortexolone 17a propionate, CB-03-01) in androgenetic alopecia
Clascoterone safely promotes hair growth similar to minoxidil.
research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice
research Usefulness of the vasodilator minoxidil in resistant hypertension
Minoxidil effectively lowers blood pressure in resistant cases, but needs beta-blocker and diuretic support.
research Microneedle-Based Codelivery of Platycladus orientalis -Derived Extracellular Vesicles and Minoxidil Nanoparticles for Androgenetic Alopecia Treatment
A new microneedle treatment combining plant-derived vesicles and minoxidil may improve hair growth for hair loss.
research Does eflornithine help women face hirsutism?
Eflornithine's effectiveness for women with facial hirsutism is unclear.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone therapy is effective and safe for women with low sexual desire, but it's hard to access.
research Assessment of male pattern androgenic alopecia with topical niosomal minoxidil
Niosomal minoxidil, when applied topically, increases hair count more than conventional minoxidil solution.
research Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro, and In Silico Studies
New compounds show promise as nonsteroidal treatments for hair loss.
research The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression
The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.
research Test yolk buffer and antisperm antibodies—interaction?
Finasteride is an effective and well-tolerated treatment for hirsutism.
research ENHANCEMENT OF FOLLICULAR DELIVERY OF FINASTERIDE IN NIOSOMALAND PRONIOSOMAL GEL FORM FOR TREATING ANDROGENETIC ALOPECIA
Finasteride, a hair loss treatment, works better and is more stable when delivered through specially prepared gels, leading to increased hair growth.