February 2026 in “NeuroSci” Finasteride and dutasteride may cause depression and anxiety, especially in younger men.
January 2026 in “Elsevier eBooks”
31 citations
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October 2013 in “Psychosomatics” Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.
January 2011 in “Reactions Weekly” St. John's Wort may reduce the effectiveness of finasteride by increasing its breakdown in the body.
11 citations
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November 2011 in “Neuroreport” Paroxetine relieves pain by increasing allopregnanolone levels.
July 2024 in “Behavioural Brain Research” Long-term finasteride treatment reduces depression and brain issues in obese male rats.
June 2019 in “Reactions Weekly”
2 citations
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July 2019 in “Journal of psychology & clinical psychiatry” Zinc helps reduce the severity of depression.
January 2012 in “The Journal of Clinical Psychiatry” 1 citations
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January 2010 in “Endocrine abstracts”
60 citations
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November 2009 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
May 2026 in “Reactions Weekly” 63 citations
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September 1995 in “Annals of internal medicine” Fluconazole can cause temporary hair loss, which stops after reducing or stopping the drug.
17 citations
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May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
25 citations
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June 2017 in “Scientific reports” Stress worsens Tourette symptoms by increasing allopregnanolone levels.
February 2026 in “Cureus” Testosterone therapy had limited benefits for a man with depression and suspected low testosterone, highlighting the need for careful diagnosis and treatment planning.
2 citations
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January 2013 in “Iraqi journal of Medical Sciences”
December 2025 in “The Journal of Clinical Psychiatry” Finasteride is not proven to cause depression or suicide, and careful patient monitoring is advised.
June 2026 in “The Journal of Sexual Medicine” Finasteride may be linked to more psychiatric issues than dutasteride, but a definite cause isn't proven.
24 citations
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May 2015 in “Schizophrenia Research” A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
1 citations
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June 2025 in “European Journal of Clinical Pharmacology” Finasteride may increase the risk of suicidality and depression, especially in younger people.
November 2020 in “Reactions Weekly” Finasteride can cause lasting erectile dysfunction, low libido, and depression in some patients.
79 citations
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January 2000 in “Annals of Clinical Psychiatry” Some psychiatric medications can cause hair loss, but stopping or reducing the dose usually reverses it.
October 2022 in “Biomolecules” Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
February 2023 in “Reactions Weekly”
8 citations
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April 2015 in “Advances in Psychosomatic Medicine” Psychotropic medications can cause skin problems but also treat some skin conditions.
3 citations
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August 2020 in “Urology Journal” Using 5-alpha reductase inhibitors may increase the risk of mild depression.
July 2025 in “Reactions Weekly”