169 citations
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August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
2 citations
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November 2011 in “Current psychiatry”
December 2006 in “Annales D Endocrinologie” Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.
11 citations
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November 2011 in “Neuroreport” Paroxetine relieves pain by increasing allopregnanolone levels.
5 citations
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January 2021 in “Inflammatory Bowel Diseases” Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.
15 citations
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September 2013 in “Pharmaceutical Biology” Jujube fruit extract may reduce kidney damage from ibuprofen in rats.
January 2008 in “xPharm: The Comprehensive Pharmacology Reference” 1 citations
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January 2010 in “SRX Pharmacology” Bupropion SR may help treat trichotillomania.
January 2022 in “Indian Journal of Psychiatry/Indian journal of psychiatry” Lithium for bipolar disorder can cause skin problems like rashes, which go away when the medication is stopped.
January 2014 in “Progress of Digestive Endoscopy” Prednisolone improved symptoms in a woman with Cronkhite-Canada syndrome, but regular screenings are needed due to cancer risk.
November 2015 in “Clin-Alert” Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
2 citations
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February 2016 in “Irish journal of psychological medicine” Mirtazapine may cause hair loss and change hair color, but stopping the drug can reverse these effects.
June 2026 in “Frontiers in Medicine” Spironolactone has the most side effects, including serious risks, while eplerenone and finerenone mainly affect the heart, kidneys, and metabolism.
8 citations
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March 2019 in “Drugs - Real World Outcomes” Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.
September 2021 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” The hormonal contraceptive combination effectively reduces androgen excess and improves PCOS symptoms like acne, hair loss, and menstrual issues.
January 2004 in “Headache” Divalproex sodium significantly improved headaches in two-thirds of patients.
August 2019 in “Repozitorij Farmaceutsko-biokemijskog fakulteta (Sveučilišta u Zagrebu)” PCOS treatment combines lifestyle changes and medication to manage symptoms and improve quality of life.
3 citations
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October 2021 in “Clinical, Cosmetic and Investigational Dermatology” Setipiprant did not significantly improve hair growth in men with hair loss.
2 citations
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December 2023 in “Journal of clinical immunology” Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.
October 2007 in “European Neuropsychopharmacology”
December 2025 in “BJPsych Open” Semaglutide may worsen eating disorders in vulnerable individuals.
January 2024 in “Frontiers in endocrinology” Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.
36 citations
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June 2014 in “Experimental Neurology” Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Finasteride and bicalutamide can affect blood sugar, so diabetics need monitoring.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Finasteride and bicalutamide can affect blood sugar, so diabetics need monitoring.
August 2025 in “Journal of Association of Clinical Endocrinologist and Diabetologist of Bangladesh” SPIOMET therapy may be a promising alternative to oral contraceptives for treating adolescent PCOS.
September 2024 in “Dermatologica Sinica” Ponatinib can cause a rare skin reaction that resolves with topical treatment and temporary drug discontinuation.
14 citations
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August 2021 in “Molecular Genetics and Metabolism Reports” Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.
May 2025 in “Birth Defects Research” YWS1903 is safe for pregnant rats at moderate doses but causes fetal issues at high doses.