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research A new label-free screen for steroid 5α-reductase inhibitors using LC-MS

15 citations , October 2016 in “Steroids”

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

research Geographic Influence and Metabolomics-Driven Discovery of 5-Alpha Reductase Inhibitors in Tectona grandis L.f. (Teak) Leaves

July 2025 in “Molecules”

Teak leaf extract can help treat hair loss, and its effectiveness varies by geographic origin.

research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors

11 citations , December 2018 in “Assay and Drug Development Technologies”

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

research RE: EFFECT OF THE DUAL 5α-REDUCTASE INHIBITOR DUTASTERIDE ON MARKERS OF TUMOR REGRESSION IN PROSTATE CANCER

3 citations , March 2005 in “The Journal of urology/The journal of urology”

Dutasteride may help shrink prostate cancer tumors.

research Anti-androgenic curcumin analogues as steroid 5-alpha reductase inhibitors

12 citations , March 2017 in “Medicinal Chemistry Research”

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

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Community Join

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community Meta analysis: Topical or mesotherapy dutasteride is more effective than topical finasteride in the treatment of AGA in men

in Research/Science 18 upvotes 4 years ago

Topical Dutasteride is more effective than topical Finasteride for treating AGA in men, with fewer side effects. Mesotherapy with Dutasteride, administered every 3 months, shows promising results for hair regrowth and maintenance without daily routines or significant side effects.

community A warning to those thinking about using Dutasteride

in Finasteride/Dutasteride 99 upvotes 6 years ago

The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.

community Effectiveness and Safety of Hair Growth Formulation Containing Tectona grandis L.f (Teak) Leaf Extract

in Chat 33 upvotes 1 year ago

Teak leaf extract shows potential as a mild hair growth promoter for androgenic alopecia, with similar positive trends to minoxidil but without significant side effects. It can be made at home using dried teak leaves and ethanol, though its effectiveness compared to other treatments like finasteride is debated.

community 38M, Topical Min 5% + Infrared Therapy (4 Months In)

in Progress Pictures 485 upvotes 1 year ago

A 38-year-old man reports positive results using topical Minoxidil 5% and infrared therapy for hair regrowth over four months, along with Saw Palmetto and Pumpkin Seed Oil supplements. Others suggest adding Finasteride for better maintenance and discuss the role of DHT blockers.

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