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research Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase 2b–3 trial

227 citations , April 2023 in “The Lancet”

Ritlecitinib effectively treats alopecia areata and is well-tolerated.

research Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata

222 citations , September 2016 in “JCI insight”

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

A Phase IIA Randomized, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of the Selective Androgen Receptor Modulator (SARM), MK-0773 in Female Participants with Sarcopenia

research A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia

211 citations , May 2013 in “Journal of Nutrition Health & Aging”

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Safety and Efficacy of Nucleic Acid Polymers in Monotherapy and Combined with Immunotherapy in Treatment-Naive Bangladeshi Patients with HBeAg Positive Chronic Hepatitis B Infection

research Safety and Efficacy of Nucleic Acid Polymers in Monotherapy and Combined with Immunotherapy in Treatment-Naive Bangladeshi Patients with HBeAg+ Chronic Hepatitis B Infection

176 citations , June 2016 in “PLoS ONE”

Nucleic acid polymers can enhance antiviral responses and improve treatment outcomes for chronic hepatitis B.

research Functional salivary gland regeneration by transplantation of a bioengineered organ germ

165 citations , October 2013 in “Nature Communications”

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

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Community Join

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community Salicylic Acid shampoo while on minoxidil. Is it okay?

in Minoxidil 12 upvotes 4 years ago

Minoxidil users can safely use salicylic acid shampoo to manage scalp pimples and dandruff. Nizoral is also recommended for hair gain and treating scalp pimples.

community Sapphire FUE vs Standard FUE: what we’ve actually seen in practice

in Hair Transplants 168 upvotes 4 days ago

Sapphire FUE uses sapphire-tipped blades for more precise incisions, but the surgeon's skill and overall procedure management are more crucial for success than the blade type. Both Sapphire and Standard FUE can yield similar results, with recovery influenced more by individual factors and aftercare than the blade used.

community Thomas Sowell's hair at age 95

in Satire 346 upvotes 3 months ago

Thomas Sowell's youthful appearance at age 95, with comments on his hair and overall looks. Some suggest using treatments like minoxidil and finasteride to maintain hair.

community Saw an opinion on PP405 and sharing

in Technology 3 months ago

PP405 is discussed as a potential adjunct therapy for hair loss, with skepticism about its effectiveness and trial results. Users mention combining it with finasteride and minoxidil for better results, while others debate the root causes of hair loss and the limitations of current treatments.

community The curious case of John Cazale’s hair

in Satire 322 upvotes 4 months ago

John Cazale's hairline showed strong recession at the temples but maintained solid volume and density, sparking discussion on different hair loss patterns and the importance of overall hair density. Treatments like Minoxidil and Spironolactone were mentioned as potential factors in maintaining hair, though genetics and styling were also considered significant.

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