research Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis, and ocular integrity in mice 32 citations , January 2016 in “Development” Sebaceous lipids are crucial for keeping skin and eyes healthy in mice.
research Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure January 2026 Lack of certain cells causes abnormal nipple development and nursing failure.
research The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis 28 citations , July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice 81 citations , February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
research Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation 34 citations , August 2019 in “Journal of Allergy and Clinical Immunology” mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.