research Loss of epidermal PLCg1 induced sebaceous gland hyperplasia and sparse hair
Removing PLCg1 from skin cells caused thicker oil glands and less hair in mice.
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research Ageing skin, part 1: normal ageing
As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
research Dynamic evaluation of pathological changes in a mouse acne model by optical imaging technology
New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.
research Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
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5 / 104 resultscommunity Is this real chat? Finasteride -> fountain of youth and longevity drug?
Finasteride is discussed as a hair loss treatment with benefits like reduced prostate enlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.
community DHT Harms Scalp Microbiome: DHT Itch is REAL
Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.
community Dutasteride at 21 years old. Is it safe?
A 21-year-old individual questioning the safety and potential side effects of using Dutasteride for hair loss, after Finasteride and RU58841 had limited effect. The responses vary, with some users suggesting it's safe and others advising to check hormone levels before proceeding.
community How is dht not beneficial to you?
DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.
community 5+ year users, what has your experience been on fin and dut?
Users discussed their experiences with hair loss treatments, primarily finasteride (Fin) and dutasteride (Dut), often combined with minoxidil (Min) and derma rolling. Many reported mixed results, with some seeing slowed hair loss and others experiencing side effects or minimal improvement.
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