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GlossarySebum Excretion Rate

amount of skin oil produced over time

The Sebum Excretion Rate (SER) refers to the amount of sebum, an oily substance produced by sebaceous glands, that is secreted onto the skin's surface over a specific period. This rate can influence skin conditions such as acne and is often measured to assess skin health and diagnose dermatological issues.

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Research

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research Effect of the gonadotrophin releasing hormone analogue, goserelin, and oestradiol replacement on sebum excretion rates and hair size in mildly hirsute women

4 citations , January 1991 in “Journal of dermatological treatment”

Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.

Changes in Serum Free Testosterone, Sleep Patterns, and 5-Alpha-Reductase Type I Activity Influence Sebum Excretion in Female Subjects

research Changes in serum free testosterone, sleep patterns, and 5‐alpha‐reductase type I activity influence changes in sebum excretion in female subjects

10 citations , August 2014 in “Skin research and technology”

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

Sebum Production: Analysis, Impact, and Measurement Methods

research Sebum Production

1 citations , September 2016 in “Springer eBooks”

Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.

research Sebum flow dynamics and antidandruff shampoos

2 citations , January 1997 in “Journal of the society of cosmetic chemists”

Different antidandruff shampoos can change how much oil your scalp produces.

research EEMCO Guidance for the in vivo Assessment of Skin Greasiness

137 citations , January 2000 in “Skin Pharmacology and Physiology”

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

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community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

in Finasteride/Dutasteride 24 upvotes 1 year ago

Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Topical Finasteride reduced my DHT more than Oral Dutasteride

in Finasteride/Dutasteride 42 upvotes 4 years ago

Treatments for hair loss, including the experiences of topical finasteride and oral dutasteride. It also discusses Pyrilutamide, 0.025% topical concentration, Minoxidil, RU58841, and 1% finasteride gel dosage.

community ~6 years on Fin + 3 years of Min. Seeing zero progress.

in Progress Pictures 228 upvotes 6 months ago

The user has been using finasteride for six years and minoxidil for three years with no noticeable hair regrowth. Suggestions include switching to dutasteride, considering a hair transplant, and trying microneedling.

community Creatine Doesn’t Cause Hair Loss: Stop the BS

in Research/Science 140 upvotes 9 months ago

Creatine does not cause hair loss, despite many users reporting personal experiences of hair shedding. Scientific evidence shows no link between creatine and increased hair loss or hormone changes.

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