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GlossarySebum Production

process where skin glands release oil to protect skin

Sebum production, also known as sebum secretion or oil production, is the process by which sebaceous glands in the skin produce and release an oily substance called sebum. This natural oil helps to lubricate and protect the skin and hair, maintaining moisture and providing a barrier against external contaminants. Overproduction of sebum can lead to oily skin and contribute to conditions like acne, while underproduction can result in dry, flaky skin.

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community sebum overproduction on fin 1mg and hair thinning

in Finasteride/Dutasteride 3 upvotes 2 years ago

User is experiencing hair thinning and sebum overproduction after starting finasteride and a hair growth supplement containing biotin, iron, zinc, and calcium. They suspect the finasteride might be fake but have noticed a side effect of watery semen.

community For people with overly oily hair, does topical finasteride/dutasteride/antiandrogens (like RU or Pyrilutamide) reduce sebum overproduction?

in Finasteride/Dutasteride 6 upvotes 3 years ago

The conversation discusses whether topical finasteride, dutasteride, or antiandrogens like RU58841 can reduce sebum overproduction as an early indicator of their effectiveness in treating hair loss. It suggests that while hair growth may take months to observe, a decrease in oiliness could be a quicker sign of a product's action.

community Topical androgens for alopecia to treat sebum overproduction on the face

in Product 1 upvotes 2 years ago

The conversation discusses using scalp antiandrogens like RU58841, pyrilutamide, or fluridil on the face to reduce sebum production, noting that clascoterone (winlevi) is an approved facial antiandrogen with underwhelming reviews.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 416 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Double Shampooing Everyday. Safe or not?

in Chat 8 upvotes 6 months ago

Double shampooing daily is safe and helps manage oily scalp and dandruff without causing hair loss. Accutane is considered for reducing sebum production despite potential temporary hair loss.

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Research

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research Updated Management of Atrophic Post Acne Scars: Review Article

October 2021 in “The Egyptian Journal of Hospital Medicine ”

Combination therapies work better than single treatments for atrophic acne scars.

research 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line

April 2019 in “Journal of Investigative Dermatology”

Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.

Hyperandrogenism Caused by Leydig Cell Tumor of the Ovary

research Hiperandrogenismo causado por tumor de células de Leydig de ovario

January 2020

A woman's excess male hormone symptoms were caused by a rare benign tumor in her ovary.

research Androgen Conjugates: Physiology and Clinical Significance

54 citations , February 1993 in “Endocrine reviews”

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Changes in Serum Free Testosterone, Sleep Patterns, and 5-Alpha-Reductase Type I Activity Influence Sebum Excretion in Female Subjects

research Changes in serum free testosterone, sleep patterns, and 5‐alpha‐reductase type I activity influence changes in sebum excretion in female subjects

10 citations , August 2014 in “Skin research and technology”

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

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