April 2026 in “Frontiers in Medicine” A 26-year-old male was initially misdiagnosed with alopecia areata but was later found to have secondary syphilitic alopecia following non-penetrative sexual contact. The patient had moth-eaten patchy alopecia and a small erythematous papule on the penile frenulum. Serological tests confirmed syphilis, with an RPR titer of 1:32 and a positive TPPA. He was treated with benzathine penicillin G, 2.4 million units intramuscularly weekly for 3 weeks, resulting in complete hair regrowth within 3 months without scarring.
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May 2022 in “Frontiers in Medicine” About 11% of patients with secondary syphilis had Syphilitic Alopecia, which usually improved with treatment.
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July 2024 in “Indian Journal of Sexually Transmitted Diseases and AIDS” Syphilitic alopecia can be effectively diagnosed and treated, leading to hair regrowth.
January 2021 in “Our Dermatology Online” A young man's hair loss was the only sign of syphilis, which improved after treatment.
11 citations
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May 2020 in “Anais Brasileiros de Dermatologia” Dermoscopy helps diagnose syphilitic alopecia, and treatment with penicillin can regrow hair.