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Glossarysecretome

collection of molecules secreted by cells into their environment

The secretome refers to the collection of molecules, such as proteins and peptides, that are secreted by cells into their surrounding environment. These molecules play crucial roles in communication between cells, tissue repair, and immune responses. For example, in the context of hair biology, the secretome of hair follicle cells can influence hair growth and regeneration.

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Research

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research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome

271 citations , May 2019 in “Cells”

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

research The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring

1 citations , March 2023 in “Pharmaceutics”

PBMCsec can help reduce and improve thick skin scars.

research The Autologous Hair Follicle and Its Secretome: A Multipotent Source for Cell-Based and Cell-Free Regenerative Therapies

May 2026 in “International Journal of Molecular Sciences”

Plucked hair follicles can be used for regenerative therapies and personalized medicine.

research Secretome-Based Therapy Promotes Epidermal Thickness Recovery and Follicular Regrowth in Fluconazole-Induced Alopecia in Rats

October 2025 in “International Journal of Cell and Biomedical Science”

hUC-MSC secretome can help regrow hair in cases of hair loss.

research Hair follicle stem cell-derived secretome protects astrocytes in an in vitro ischemia/reperfusion model

March 2025 in “Anatomy & Cell Biology”

Hair follicle stem cell secretions may help protect brain cells and improve stroke recovery.

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community New Hair Loss Treatment: Adipose Derived Secretomes

in Research/Science 17 upvotes 1 year ago

Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

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