Search

for
Search:

Did you mean Selective Estrogen Receptor Modulators?

GlossarySelective Estrogen Receptor Modulators

modulate estrogen effects in different tissues selectively

Selective Estrogen Receptor Modulators (SERMs) are a class of compounds that act on the estrogen receptor. They can either block or activate estrogen's effects in different tissues, depending on the specific SERM and the tissue type. For example, they might block estrogen's action in breast tissue to reduce the risk of breast cancer, while activating it in bone tissue to help maintain bone density.

Related Terms

Research

5 / 1000+ results

research Family planning 2011: better use of existing methods, new strategies and more informed choices for female contraception

11 citations , June 2012 in “Human Reproduction Update”

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

research Relating neurosteroid modulation of inhibitory neurotransmission to behaviour

18 citations , September 2021 in “Journal of Neuroendocrinology”

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

research Chapter 17. Selective androgen receptor modulators (SARMs)

18 citations , January 2001 in “Annual Reports in Medicinal Chemistry”

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

research Effect of estrogens on skin aging and the potential role of selective estrogen receptor modulators

67 citations , January 2007 in “Climacteric”

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

research Improving selective androgen receptor modulator discovery and preclinical evaluation

11 citations , August 2009 in “Expert Opinion on Drug Discovery”

We need better ways to test and understand SARMs to make safer and more effective treatments.

View more "selective progesterone receptor modulators" in research →

Community Join

5 / 1000+ results

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 4 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 2 years ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 94 upvotes 6 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 57 upvotes 2 years ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 71 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

View more "selective progesterone receptor modulators" in community →

Learn

1 / 801 results

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

View more "selective progesterone receptor modulators" in learn →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →