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research Dermatologic Effects of Selumetinib in Pediatric Patients with Neurofibromatosis Type 1: Clinical Challenges and Therapeutic Management

15 citations , March 2024 in “Journal of Clinical Medicine”

Selumetinib causes skin and hair side effects in kids with NF1, affecting treatment and quality of life.

research Cutaneous Toxicities of MEK Inhibitor Use in Children: A Comparison of Binimetinib and Selumetinib

3 citations , November 2024 in “Pediatric Dermatology”

Selumetinib causes fewer and less severe skin issues in children than binimetinib.

research Visual Improvement in a Child With Periorbital Plexiform Neurofibroma Treated With Selumetinib: Case Report and Literature Review

August 2025 in “Ophthalmic Plastic and Reconstructive Surgery”

Selumetinib significantly reduced tumor size and improved vision in a child with neurofibromatosis type 1.

Pharmacotherapy of Plexiform Neurofibromas in Patients with Neurofibromatosis Type 1: Possible Adverse Events and Their Management

research Pharmacotherapy of plexiform neurofibromas in patients with neurofibromatosis type 1. Possible adverse events and their management

July 2024 in “Russian Journal of Child Neurology”

Selumetinib effectively reduces tumor size in many children with neurofibromatosis type 1, but can cause skin and hair issues.

BAYONET Trial: Staged Combination With Encorafenib, Binimetinib, Plus Cetuximab Following Encorafenib Plus Cetuximab for BRAF V600E-Mutant Metastatic Colorectal Cancer

research BAYONET trial: staged combination with encorafenib, binimetinib, plus cetuximab following encorafenib plus cetuximab for BRAF V600E-mutant metastatic colorectal cancer

June 2024 in “ESMO Gastrointestinal Oncology”

The combination treatment showed a higher response rate but no significant survival benefits.

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Learn

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learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

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community Ruxolitinib - Start of a case study

in Research/Science 10 upvotes 2 years ago

The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

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