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Dermoscopy helps diagnose syphilitic alopecia, and treatment with penicillin can regrow hair.

Syphilis can cause hair loss and should be considered in unexplained cases.

Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.

Syphilis can cause hair loss without other symptoms and should be considered when diagnosing unexplained hair loss.

HIV-infected men who have sex with men are at higher risk for aggressive syphilis, but treatment and tests are effective.