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research Genetically Induced Cell Death in Bulge Stem Cells Reveals Their Redundancy for Hair and Epidermal Regeneration

13 citations , December 2014 in “Stem Cells”

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

research Genetically modified laboratory mice with sebaceous glands abnormalities

22 citations , July 2016 in “Cellular and Molecular Life Sciences”

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

research c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis

60 citations , February 2013 in “Cell reports”

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

research Epigenetic control of adult stem cell function

179 citations , July 2016 in “Nature Reviews Molecular Cell Biology”

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

research Stem Cell Heterogeneity and Plasticity in Epithelia

129 citations , May 2015 in “Cell Stem Cell”

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

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