research Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis 65 citations , November 2013 in “The EMBO Journal” HDAC1 is crucial for skin development and preventing tumors.
research The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor 178 citations , October 2001 in “Genes & Development” The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.
research Hairless: A nuclear receptor corepressor essential for skin function January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets. 39 citations , January 2016 in “PubMed” Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
research Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ 11 citations , July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.