March 2025 in “Asian Journal of Beauty and Cosmetology” The study investigated the skin improvement efficacy of microspicule cosmetics containing low-molecular-weight peptide complexes. An in vitro test showed excellent cell viability and a 23.62% inhibition rate of melanogenesis at 0.1% concentration. A human application test on 20 adults aged 30–59 over 4 weeks revealed significant improvements in skin whitening, pore improvement, and skin barrier enhancement, with the experimental group showing superior results compared to the comparison group. The findings suggest that microspicules enhance the transdermal absorption of active ingredients, strengthening the skin barrier and providing a basis for optimizing spicule purification techniques and cosmetic formulations for skin safety and efficacy.
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February 2024 in “International journal of molecular sciences” Hesperidin from orange peels is a promising natural ingredient for skincare due to its multiple beneficial properties.
120 citations
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July 2005 in “Dermatologic surgery” Niacinamide improves aging skin and is safe for use in cosmetics.
November 2019 in “Harper's Textbook of Pediatric Dermatology” The document is a detailed medical reference on skin and genetic disorders.
Polyglutamic acid is a valuable, sustainable ingredient for skincare and haircare products.