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research Emerging nonmetabolic functions of skin fat

65 citations , January 2018 in “Nature Reviews Endocrinology”

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

research Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages

6 citations , December 2022 in “Cell reports”

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

research The Fate of Epidermal Tight Junctions in the stratum corneum: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions

11 citations , July 2022 in “International Journal of Molecular Sciences”

Tight junctions help control skin shedding and may be targets for treating certain skin conditions.

research The fatty acids and the skin: a focus on the n-6 family of unsaturated fatty acids

1 citations , January 2012 in “Human health handbooks”

Linoleic acid is important for healthy skin, and while most people get enough from their diet, not having enough can cause skin and hair problems.

research Gut Microbiota Shapes the Effects of Saturated and Polyunsaturated Fatty Acids on Skin and Hair Follicle Homeostasis

July 2026 in “Journal of Investigative Dermatology”

Gut microbes influence how different fats affect skin and hair health.

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community Did Dutasteride change how you look physically? your facial profile such as skin thickness, fat distribution or softness?

in Finasteride/Dutasteride 51 upvotes 1 year ago

Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.

community Can this fate be avoided? Or must i simply accept it.

13 years ago

A 19-year-old is experiencing early hair loss, possibly due to oily skin, stress, poor diet, and lack of sleep. They have tried ketoconazole shampoo without success and plan to visit a dermatologist for further advice.

community Injecting stomach fat into the scalp could cure baldness in just six months

in Update 114 upvotes 7 years ago

A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

community Bimatoprost vs Latanoprost for scalp hair growth

in Treatment 1 upvotes 4 months ago

Bimatoprost and latanoprost are being considered for scalp hair growth, with concerns about side effects like skin darkening and fat loss. A user warns about potential chemical burns from latanoprost.

community Experiencing Side Effects After 6 Months on Finasteride - Continue or Stop?

in General 137 upvotes 11 months ago

The user experienced positive hair growth with finasteride but developed gut issues, dry skin, thinning eyebrows, fatigue, low libido, and erection difficulties after stopping it. They are seeking advice on whether to resume finasteride or stay off it to recover.

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