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research Application of genetically modified umbilical cord blood cells and direct gene therapy for treatment of skin wounds in rats

September 2014 in “Genes and Cells”

Genetically modified umbilical cord blood cells improved skin wound healing in rats.

research Enhancing 1α-Hydroxylase Activity with the 25-Hydroxyvitamin D-1α-Hydroxylase Gene in Cultured Human Keratinocytes and Mouse Skin

18 citations , June 2001 in “Journal of Investigative Dermatology”

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

research Gene Therapy: Recent Advances and Applications in Dermatology

1 citations , October 1996 in “Journal of Cutaneous Medicine and Surgery”

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

research 478 Mutation-specific siRNA Knockdown of GJB2 − Potential gene therapy for Keratitis-ichthyosis-deafness Syndrome

April 2017 in “Journal of Investigative Dermatology”

Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.

research The effects of transfection of human VEGF165 gene with electroporatic technique into bleomycin-induced sclerotic skin in mice

January 2005 in “Linchuang pifuke zazhi”

The technique successfully promoted hair growth and skin renewal in mice.

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community Minoxidil and skin aging worry - which prevention methods (platelet rich plasma, microneedlig, mesotherapy, stem cells, co2, ultherapy, ...)

in Chat 4 upvotes 3 years ago

User started minoxidil, noticed forehead lines and dark circles, and asked for non-invasive skin aging prevention methods. Another user suggested using tretinoin and hyaluronic acid for long-term benefits.

community Researchers working on ways to regenerate lost hair from stem cells identified a recipe for normal hair regeneration in the lab. “A method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future.”

in Research/Science 258 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 4 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 10 months ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

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