research Small Molecule Agents Against Alopecia: Potential Targets and Related Pathways
New small molecule drugs could help treat hair loss.
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5 / 1000+ resultsresearch A translational approach to improve therapeutics in atopic dermatitis and beyond
New treatments for atopic dermatitis and alopecia areata have been developed using a targeted approach.
research Pathophysiological mechanisms of hair follicle regeneration and potential therapeutic strategies
Understanding hair growth pathways can lead to better hair loss treatments.
research Wnt/β‐catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration
The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
research A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis
DRDE-07 shows promise for treating skin diseases due to its favorable properties.
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5 / 1000+ resultscommunity A New Therapeutic Channel to Come Soon: Hair Follicle Sugar Metabolism and Aldose Reductase
Hair loss therapies focusing on hair follicle sugar metabolism and aldose reductase. Potential treatments include magnesium supplements, avoiding high glycemic index foods, and antioxidants.
community Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results
ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.
community 2 % fucoidan significantly alleviated AGA symptoms, promoted hair growth, and increased hair density
2% fucoidan alleviated AGA symptoms, promoted hair growth, and increased hair density in mice. Fucoidan is considered safe for humans as a supplement and topical skincare product, with potential therapeutic effects against AGA.
community All Drugs in Clinical Trials in 2023
12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.
community GT20029 China Phase II Trial For AGA Reached Primary Endpoint
The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
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4 / 801 resultslearn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
learn Exosomes
Microscopic delivery system that sends growth-promoting signals to hair follicles
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Stem Cell Factor
Experts
6 / 7 results- 55SMP Specialist
Joe Small
Kirkcaldy, United Kingdom
- 51
Hair System SpecialistMarlisa Small
Little River, SC, United States
- 27Hair Transplant Surgeon
Dr. Bob Smeele
Capelle aan den IJssel, Netherlands
- 68
Hair Loss SpecialistJeanette Szemela
Bratislava, Slovakia
- 86
Hair Transplant SurgeonDr. Zbigniew Smyła, MD
Tychy, Poland
- 94
Hair Transplant SurgeonDr. Shamila Rawal, MD
Madison, WI, United States