research The investigation of selective sphingosine-1 phosphate receptor 1&4 modulator to treat alopecia areata mouse model 2881 November 2025 in “The Journal of Immunology” The S1PR 1&4 modulator may effectively treat alopecia areata by reducing hair loss and immune cell activity.
research The investigation of selective sphingosine-1 phosphate receptor 1&4 modulator to treat alopecia areata mouse model 2 citations , May 2023 in “The Journal of Immunology” NXC736 significantly reduced hair loss in mice with alopecia areata.
research Etrasimod for alopecia areata: The scenario for a less extensive and moderate form May 2025 in “Journal of the European Academy of Dermatology and Venereology” Etrasimod is safe but not effective for severe alopecia areata, though it may help milder cases.
research Author response: The signaling lipid sphingosine 1-phosphate regulates mechanical pain 1 citations , January 2018 Sphingosine 1-phosphate and its receptor S1PR3 are key in controlling mechanical pain.
research Decision letter: The signaling lipid sphingosine 1-phosphate regulates mechanical pain December 2017 Sphingosine 1-phosphate helps control mechanical pain.