The conversation discusses using S5 plus cream (Spironolactone, Alfatradiol, and Tempol) as an alternative to finasteride for hair loss, with concerns about its effectiveness and potential systemic absorption. The original poster already uses 5% minoxidil and is seeking alternatives due to fears of finasteride's side effects.
User asks about topical spironolactone experience. Two studies show it as promising anti-androgen treatment, with 5% cream available on Minoxidilmax website.
A user shared a guide for mixing a topical spironolactone solution for hair loss, using ingredients like spironolactone tablets, ethyl alcohol, and propylene glycol. They compared it to the S5 cream, finding their homemade solution more practical and cost-effective.
The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactonecream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.