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research Matrix matching in quantitative bioanalysis by LC–MS/MS a dream or a reality?
Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.
research Simultaneous determination of multi-class active pharmaceutical ingredients by UHPLC-HRMS
A new method was developed to accurately detect and measure 47 different drug ingredients in various products.
research Production rates of testosterone and of dihydrotestosterone in female pattern hair loss
Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.
research Matrix effects and application of matrix effect factor
Matrix effects in LC-MS can be managed but not completely avoided.
research Improving stable isotopic interpretations made from human hair through reduction of growth cycle error
The conclusion is that recognizing hair growth cycles can improve the precision of dietary and health assessments from hair analysis.
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5 / 1000+ resultscommunity Sugar and Hair loss connections
High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.
community Dutasteride Literally Saves Your Hair
Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.
community Hairline stable but diffuse thinning with topical fin+min
The user experienced stable hairline but diffuse thinning after switching from oral finasteride to a topical solution of minoxidil and finasteride. They are concerned about the effectiveness of the topical treatment and are considering other options due to a recent decline in hair density.
community 18 y/o – stable hairline with topical fin (Fynzur), Minoxidil & Dermastamp – add oral Finasteride as prevention?
An 18-year-old is maintaining a stable hairline using Minoxidil, topical finasteride (Fynzur), and Dermastamp, and is considering adding oral finasteride for prevention. They seek advice on whether starting oral finasteride early is necessary given their family history and current regimen.
community Hair loss stable for 8+ years – is it still possible to regrow, or should I just accept it?
A user is considering starting treatments like Finasteride, Minoxidil, and Microneedling for hair thinning, despite stable hair loss for over 8 years. They are unsure if the presence of miniaturized hairs indicates potential for regrowth or if they should accept the current state.