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research Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations

178 citations , April 2011 in “Journal of Clinical Investigation”

Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.

Equine Hoof Stem Progenitor Cells (HPC) CD29+/Nestin+/K15+ – A Novel Dermal/Epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment

research Equine Hoof Stem Progenitor Cells (HPC) CD29 + /Nestin + /K15 + – a Novel Dermal/epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment

6 citations , May 2021 in “Stem Cell Reviews and Reports”

Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.

research Defining compartmentalized stem and progenitor populations with distinct cell division frequency in the ocular surface epithelium

June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Stem and progenitor cells in the eye have different division rates and locations, affecting how they respond to injury.

research Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells

April 2010 in “Cancer Research”

Stat3 activation increases hair follicle progenitors but reduces bulge region stem cells.

research Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations

23 citations , September 2013 in “Molecular Carcinogenesis”

Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.

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community A Theory on Why Microneedling Works

172 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

in Research/Science 5 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Is PP405 gonna flop or what???

in Research/Science 3 months ago

PP405 is viewed skeptically, with some seeing it as overhyped and potentially ineffective compared to existing treatments like minoxidil and finasteride. While it shows some promise in activating dormant hair follicles, many believe it won't replace hair transplants or significantly outperform current options.

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learn Stem Cell Factor

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29
Hair Transplant Surgeon
Dr. Sten Thure Eriksen
Oslo, Norway
25+ yrs

Dr. Sten Thure Eriksen