Search

for
Search:

Research

5 / 1000+ results

research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.

53 citations , June 1993 in “Proceedings of the National Academy of Sciences of the United States of America”

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Pharmacokinetic Parameters and Mechanisms of Inhibition of Rat Type 1 and 2 Steroid 5α-Reductases: Determinants for Different In Vivo Activities of GI198745 and Finasteride in the Rat

research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.

22 citations , October 2001 in “Biochemical Pharmacology”

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase

research Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase

8 citations , June 1995 in “Helvetica Chimica Acta”

Compound 15a was effective in inhibiting 5α-reductase.

research Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes

186 citations , December 2011 in “Molecules”

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

research A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization

4 citations , November 2022 in “Frontiers in endocrinology”

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

View more "steroid 12" in research →

Community Join

5 / 861 results

community 12 months of treatment and some questions I have

in Basic Questions 279 upvotes 6 days ago

The user has been using finasteride and oral minoxidil for hair loss, but experienced increased hair loss after using testosterone steroids without post-cycle therapy. They are considering switching to dutasteride and have added ketoconazole shampoo to their routine, but are concerned about side effects and the ongoing hair loss.

community 1 month on min and derma pen every 10 days. Can you see a difference?

in Is this regrowth? 111 upvotes 1 year ago

A user has been using 5% minoxidil and a derma pen for one month, experiencing shedding but noticing potential new hair growth. They plan to add finasteride to their regimen.

community officially 1 full year on min and dutasteride

in Progress Pictures 964 upvotes 2 years ago

The user shared a one-year progress of hair regrowth using topical minoxidil and dutasteride, along with microneedling and scalp massages. They experienced significant hair growth without side effects.

community 1 mg oral finasteride results for 16 months (planning to switch to dutasteride)

in Finasteride/Dutasteride 23 upvotes 1 year ago

The user has been using 1 mg oral finasteride for 16 months to slow hair loss and is considering switching to dutasteride due to continued hair shedding. They are avoiding oral minoxidil due to potential side effects and are exploring other options with a dermatologist.

community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

View more "steroid 12" in community →