research In Vivo Time-Dependent Inhibition of Human Steroid 5a-Reductase by Finasteride
Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
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research Cloning, computational analysis and expression profiling of steroid 5 alpha-reductase 1 (SRD5A1) gene during reproductive phases and ovatide stimulation in endangered catfish, Clarias magur
The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
research Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase
New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
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5 / 863 resultscommunity Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate.
Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.
community Finasteride does deplete important nuero-active steroids
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.
community What happens to the excess testosterone after using dut?
Using dutasteride or finasteride can increase free testosterone, which may convert to estradiol, potentially causing side effects like increased estrogen levels. Individual responses vary, and some users report changes in cholesterol, hair texture, and side effects like gyno or increased sex drive.
community Hormonal Imbalance Theory and the "Trash Hormone"...
Balancing hormones, particularly testosterone and DHT, may prevent hair loss and slow aging. Treatments include finasteride, dutasteride, zinc, magnesium, collagen, and natural DHT-blocking shampoos.
community Possible explanation of why Dutasteride seems to be worse for some people’s hair.
The conclusion of the conversation is that some individuals may experience a condition called reactionary hypergonadism when taking dutasteride for hair loss. This condition can lead to an increase in testosterone levels, which may worsen hair loss instead of improving it.
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2 / 801 resultslearn dehydroepiandrosterone
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a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
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Hair SystemsTrichologyStrut Hair SolutionsCardiff, CA · US - 24Hair Loss TreatmentsStraight from RioKristiansand · NO
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Hair TransplantStuart Lipton, MDLewisville, TX · US - 17
Hair Loss TreatmentsHair TransplantHarley Street Hair and Skin Care ClinicsBristol · GB - 30
Hair TransplantHarley Street HealthcareLondon · GB
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Hair Loss SpecialistJohn W. Mowinckel Storlid
Málaga, Andalucia, Spain
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Hair Loss SpecialistJohn W. Mowinckel Storlid
Bergen, Norway
- 18SMP Specialist
Stuart Buckley
Manchester, United Kingdom
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Stuart Mundy
Southampton, United Kingdom
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Hair Transplant SurgeonDr. Siddharth Mendiratta, MBBS, MS, MCh, DNB
Nagpur, Maharashtra, India
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Hair Transplant SurgeonSiddhartha Chatterjee, MDS
Kolkata, West Bengal, India