41 citations
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April 2006 in “Hormone and metabolic research” Steroid-binding globulins have important roles beyond just transporting steroids.
16 citations
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January 2010 in “Drug Metabolism and Pharmacokinetics” Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
Women with androgenetic alopecia have normal levels of most blood steroids and binding proteins, but higher dehydroepiandrosterone. Some also have low "sex hormone-binding globulin" and "corticosteroide-binding globulin" capacity, and high "free androgen index" and "free cortisol index". Diane treatment can normalize these levels and improve hair conditions.
2 citations
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October 1988 in “Steroids” Certain hormone treatments can increase SBP levels and help with mild body hair growth.
35 citations
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September 1972 in “Journal of Biological Chemistry” Steroid hormone binding in rat skin varies with pH, heat, and hair cycle phases.