learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 9 resultslearn Overview
learn Epidermal Growth Factor
learn Caffeine
the stimulant you know and love can be used topically to stimulate hair
learn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
Research
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research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Stress and the Hair Growth Cycle: Cortisol-Induced Hair Growth Disruption.
High stress can disrupt hair growth, but certain supplements might help.
research Stress-related skin disorders
Stress can worsen skin conditions by affecting hormone levels and immune response.
research A case of MBTPS1 ‐related disorder due to compound heterozygous variants in MBTPS1 gene: Genotype–phenotype expansion and the emergence of a novel syndrome
A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
Community Join
5 / 1000+ resultscommunity Keratin microspheres - breakthrough
A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.
community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System
PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.
community 26F Thinner hair due to vitamin deficiencies?
A female user with chronic anemia and vitamin deficiencies is experiencing finer, straighter hair and seeks recommendations for scalp products to improve circulation and prevent potential hair thinning. She is considering growth oils but is unsure of their effectiveness.
community Why is Minoxidil not enough for hair loss? (No fin)
Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.
community Confused why people are calling PP405 a cure...it never claimed to be able to undo miniaturization or revert vellus back to terminal hairs. It seems to be more of a growth stimulant like minoxidil.
PP405 is not a cure for hair loss but may reactivate dormant hair follicles, similar to minoxidil. It is unlikely to help with miniaturized or vellus hairs and is still in trial phases, with availability expected around 2030.