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      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn GT20029

      research compound made to degrade androgen receptors in scalp

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      community My home made topical dutasteride

      in Finasteride/Dutasteride  3 upvotes 1 year ago
      The conversation is about a user making a homemade topical dutasteride solution to use alongside testosterone replacement therapy (TRT) and oral dutasteride. The user aims to reduce DHT locally at the testosterone injection site and on the scalp.

      community My Estradiol Level on Finasteride

      in Research/Science  19 upvotes 9 months ago
      Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

      community Nandrolone Replacement Therapy

      in Treatment  44 upvotes 2 years ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.