research TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis 91 citations , June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function 22 citations , September 2011 in “Journal of Investigative Dermatology” TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation 990 citations , October 1999 in “Development” Activated LEF/TCF complexes are crucial for hair development and cycling.
research Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells 384 citations , June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
research Faculty Opinions recommendation of The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. April 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The vitamin D receptor helps control hair growth and may protect against certain skin tumors.
community The Real Cause Of Androgenetic Alopecia in Research/Science 677 upvotes 1 year ago Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.