research Adverse Reactions to Oral Retinoids An Update 53 citations , October 1993 in “Drug Safety” Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
research Actions of isotretinoin and etretinate on the pilosebaceous unit 46 citations , April 1982 in “Journal of the American Academy of Dermatology” Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.