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Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions

research Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions

September 2023 in “Journal of Nutrition and Metabolism”

One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.

Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

326 citations , February 2009 in “The American journal of pathology”

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

research Comparative Characterization of Hair Follicle Dermal Stem Cells and Bone Marrow Mesenchymal Stem Cells

151 citations , February 2006 in “Stem Cells and Development”

Hair follicles can be a good source of stem cells like those from bone marrow.

research Editorial: Directing Stem Cell Fate Using Plant Extracts and Their Bioactive Compounds

4 citations , June 2022 in “Frontiers in Cell and Developmental Biology”

Plant extracts might help control stem cell growth for medical use.

research 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG) from Polygonum multiflorum Thunb.: A Systematic Review on Anti-Aging

3 citations , April 2025 in “International Journal of Molecular Sciences”

TSG from Polygonum multiflorum may help with anti-aging by protecting the brain, heart, bones, and hair.

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community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 4 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community Hair loss research is a money grab

in Chat 227 upvotes 8 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community Creatine effects on DHT Experiment

in Research/Science 58 upvotes 2 years ago

Creatine might increase hair loss due to increased DHT sensitivity, but evidence is mostly anecdotal. The user is using oral minoxidil for hair loss and is cautious about starting creatine.

community In my opinion baldness is more prevalent now and it's being ignored..

in Chat 236 upvotes 2 years ago

The conversation is about the prevalence of baldness among young men and the potential factors contributing to it. Specific treatments mentioned include minoxidil and finasteride.

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