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research Conditional telomerase induction causes proliferation of hair follicle stem cells

414 citations , August 2005 in “Nature”

Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.

research Faculty Opinions recommendation of Conditional telomerase induction causes proliferation of hair follicle stem cells.

October 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Activating telomerase can boost hair follicle stem cell growth and hair production.

Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease

research Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease

11 citations , January 2000 in “Journal of Cutaneous Pathology”

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Telomere Dysfunction Impairs Epidermal Stem Cell Specification and Differentiation by Disrupting BMP/pSmad/P63 Signaling

research Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling

19 citations , September 2019 in “PLOS genetics”

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

Increased Copy Number of the TERT and TERC Telomerase Subunit Genes in Cancer Cells

research Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

145 citations , May 2008 in “Cancer Science”

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

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