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research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research

12 citations , January 2021 in “Journal of Investigative Dermatology”

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

research Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita

3 citations , April 2025 in “Science Advances”

Loss of Ten1 in mice causes telomere shortening and symptoms similar to human dyskeratosis congenita.

research Normal and Aging Hair Biology and Structure ‘Aging and Hair'

20 citations , January 2015 in “Current problems in dermatology”

Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.

research Appearance and Internal Aging

September 2016 in “Springer eBooks”

Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.

research Le vieillissement de la peau et du follicule pileux : de la caractérisation clinique à l'étude fonctionnelle

1 citations , April 2015 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)”

Skin and hair aging involves mitochondrial issues, telomere shortening, and hormonal changes, with iron affecting hair loss in pre-menopausal women.

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community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.

in Research/Science 47 upvotes 1 year ago

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

community Is this real chat? Finasteride -> fountain of youth and longevity drug?

in Finasteride/Dutasteride 558 upvotes 10 months ago

Finasteride is discussed as a hair loss treatment with benefits like reduced prostate enlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.

community Pyrilutamide just launched internationally, and all you're doing is hating

in Product 1 year ago

The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

community Hair loss research is a money grab

in Chat 227 upvotes 8 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 3 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

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