research Th1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata May 2025 CD4 T cells need IFN-γ to cause hair loss in alopecia areata.
research T H 1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata October 2025 in “Science Advances” IFN-γ production by CD4 T cells is crucial for causing alopecia areata.
research Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment 278 citations , March 2013 in “Gut” Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region as Well as the Hair Bulb Area in the Chronic Alopecia Areata Patients 18 citations , January 2017 in “Annals of dermatology/Annals of Dermatology” Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
research Olink proteomics analysis of scalp psoriasis reveals a cytokine storm inflammatory mainly related to bacterial-derived antigens July 2025 Scalp psoriasis inflammation is mainly caused by bacteria-related triggers.
learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss