17 citations
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April 2023 in “Aging” CNGA3, GLUD1, and SIRT1 are promising targets for treating aging and glioblastoma.
2 citations
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July 2025 in “Frontiers in Veterinary Science” This review discusses the critical role of microRNAs (miRNAs) in regulating hair follicle development and cycling in cashmere goats, which are prized for their fine fiber. It highlights the influence of key miRNAs, such as miR-31, miR-22, and miR-214, on hair follicle morphogenesis, regeneration, and fiber traits. Recent advances in single-cell RNA sequencing and spatial transcriptomics have provided new insights into cellular heterogeneity and lineage specification. Integrative multi-omics approaches reveal complex regulatory networks involving miRNAs, while AI-driven analytics enhance biomarker discovery and therapeutic target identification. These findings inform breeding strategies to improve cashmere fiber quality and offer minimally invasive diagnostic tools for hair disorders. Future directions include improved miRNA delivery methods and AI-powered multi-omics approaches to advance hair follicle biology understanding and practical applications in medicine and agriculture.
January 2017 in “Brazilian Journal of Pharmaceutical Sciences” Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.
15 citations
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November 2022 in “Cell Death and Disease” CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.
24 citations
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December 2009 in “Future Medicinal Chemistry” Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.