research First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases 103 citations , January 2011 in “Blood” Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
research Human FOXN1-Deficiency Is Associated with αβ Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation 32 citations , May 2012 in “PloS one” Thymic transplantation normalized some T-cells but not others, maintaining immune function.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program 69 citations , January 2013 in “Frontiers in Immunology” The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research FOXN1 deficient nude severe combined immunodeficiency 32 citations , January 2017 in “Orphanet journal of rare diseases” FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss 7 citations , January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cell reconstitution after thymus transplantation can cause hair whitening and loss.