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research 068 Pathogenic Th17 cells, CD8+CD69+CD49a- tissue-resident memory T cells and common γ chain receptor + natural killer cells express more IL-17, compared to IFN-γ, under the foxp3+ memory regulatory T cells-depleted microenvironment in patients with chronic alopecia areata

April 2023 in “Journal of Investigative Dermatology”

IL-17 plays a key role in severe hair loss in chronic alopecia areata.

research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease

9 citations , March 2022 in “Frontiers in Immunology”

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

research Modulating the stem cell niche for tissue regeneration

480 citations , August 2014 in “Nature Biotechnology”

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

research Predominant expression of interleukin (IL)‐17 in chronic alopecia areata compared to IFN‐γ in pathogenic Th17 cells, tissue‐resident memory T cells and natural killer cells

3 citations , January 2023 in “JEADV Clinical Practice”

IL-17 is more important than IFN-γ in causing severe hair loss in chronic alopecia areata.

research Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration

188 citations , March 2018 in “Frontiers in Immunology”

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

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community Apparently you can try PP405 right now!?

in Research/Science 33 upvotes 1 year ago

PP405 is likely a scam, with concerns about its legitimacy and safety, as it may cause unintended tissue growth. Users suggest sticking to known treatments like finasteride and minoxidil.

community Update and new paper from Dr tsuji

in Update 25 upvotes 7 years ago

Hair follicle regenerative therapy is being developed, with clinical trials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.

community Summary of Procapil video by Haircafe

in Minoxidil 2 upvotes 1 year ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

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