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research Novel TMEM173 Mutation and the Role of Disease Modifying Alleles

47 citations , December 2019 in “Frontiers in immunology”

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

research Characterization of novel TMEM173 mutation with additive IFIH1 risk allele

1 citations , August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

research Regulation of Tmem30b-mediated apical membrane homeostasis in auditory outer hair cells is critical for hearing

April 2026 in “Proceedings of the National Academy of Sciences”

Tmem30b is essential for hearing by maintaining hair cell structure in the ear.

research 1393 Human TMEM2 is not a hyaluronidase but a regulator of hyaluronan metabolism

April 2023 in “Journal of Investigative Dermatology”

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

research 034 Characterization of novel TMEM173 mutation causing a lupus- and SAVI-like phenotype, modified by polymorphisms in TMEM173 and IFIH1

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.

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community Blaming Finasteride doesn't help you solve anything: dry eyes

in Finasteride/Dutasteride 51 upvotes 1 year ago

Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.

community Roughly 1.5 years of treatment, don't give up!

in Progress Pictures 503 upvotes 3 months ago

The user shared their hair regrowth journey using finasteride, oral minoxidil, and dutasteride over 1.5 years, showing significant improvement. They experienced no side effects and noted increased body hair growth with oral minoxidil.

community Bro in law. Gave up because he hated dermarolling and genuinely didn't care about going bald, which he suits.

in Progress Pictures 65 upvotes 2 years ago

The conversation discusses hair loss treatment using 1ml of minoxidil twice daily and a 1.5mm dermaroller once a week. One person suggests considering finasteride, while another emphasizes the importance of microneedling in maintaining hair growth.

community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.

in Research/Science 156 upvotes 1 year ago

GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.

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