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    Did you mean TNF inhibitors?
    GlossaryTNF inhibitors

    medications that block inflammation-causing proteins in autoimmune diseases

    TNF inhibitors, also known as Tumor Necrosis Factor inhibitors or TNF blockers, are medications that reduce inflammation by blocking the activity of TNF-alpha, a substance in the body that causes inflammation and can lead to immune system diseases. They are commonly used to treat autoimmune conditions such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease by preventing the immune system from attacking healthy tissues.

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      community Finasteride does deplete important nuero-active steroids

      in Research/Science  11 upvotes 2 years ago
      Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 4 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  53 upvotes 1 week ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Rejected for the 2nd time for the VDPHL01 Clinical Trials (believe it or not!)

      in Chat  12 upvotes 1 year ago
      The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.