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Comparative Evaluation of Efficacy and Safety of Topical Methotrexate With Tretinoin Versus Betamethasone With Tretinoin in Patients of Alopecia Areata: A Prospective Randomized Double-Blind Study

research COMPARATIVE EVALUATION OF EFFICACY AND SAFETY OF TOPICAL METHOTREXATE WITH TRETINOIN VERSUS BETAMETHASONE WITH TRETINOIN IN PATIENTS OF ALOPECIA AREATA: A PROSPECTIVE RANDOMIZED DOUBLE-BLIND STUDY

October 2024 in “Asian Journal of Pharmaceutical and Clinical Research”

Topical methotrexate is more effective and as safe as betamethasone for treating alopecia areata.

Comparison of the Efficacy of Topical Methotrexate 1% Gel Versus Topical Betamethasone Dipropionate 0.05% Lotion in the Treatment of Localized Scalp Alopecia Areata in a Tertiary Care Institute of Central India: A Randomized Control Trial

research Comparison of the Efficacy of Topical Methotrexate 1% gel Versus Topical Betamethasone Dipropionate 0.05% Lotion in the Treatment of Localized Scalp Alopecia Areata in a Tertiary Care Institute of Central India: A Randomized Control Trial

August 2025 in “Indian Dermatology Online Journal”

Both treatments work equally well for hair regrowth, but the lotion has fewer side effects.

Successful Therapy of Alopecia Universalis Using a Combination of Systemic Methotrexate and Corticosteroids and Topical 5% Minoxidil

research Successful Therapy of Alopecia Universalis Using a Combination of Systemic Methotrexate and Corticosteroids and Topical 5% Minoxidil

January 2022 in “Clinical, Cosmetic and Investigational Dermatology”

A mix of methotrexate, corticosteroids, and topical minoxidil effectively treated severe total body hair loss, but caused stretch marks and needs long-term monitoring.

research Evaluation of methotrexate-loaded surfactants, ceramides and cholesterol-based lamellar phases as a topical treatment for psoriasis

2 citations , February 2022 in “Journal of Pharmacy and Pharmacology”

Methotrexate-loaded formulations showed promise for psoriasis treatment but need careful evaluation.

research A rare case of multiple keratoacanthomas treated with oral acitretin and intralesional methotrexate

5 citations , January 2016 in “Indian dermatology online journal”

A 25-year-old man with multiple skin tumors was successfully treated with acitretin and methotrexate.

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community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 1 year ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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research COMPARATIVE EVALUATION OF EFFICACY AND SAFETY OF TOPICAL METHOTREXATE WITH TRETINOIN VERSUS BETAMETHASONE WITH TRETINOIN IN PATIENTS OF ALOPECIA AREATA: A PROSPECTIVE RANDOMIZED DOUBLE-BLIND STUDY

research Comparison of the Efficacy of Topical Methotrexate 1% gel Versus Topical Betamethasone Dipropionate 0.05% Lotion in the Treatment of Localized Scalp Alopecia Areata in a Tertiary Care Institute of Central India: A Randomized Control Trial

research Successful Therapy of Alopecia Universalis Using a Combination of Systemic Methotrexate and Corticosteroids and Topical 5% Minoxidil

research Evaluation of methotrexate-loaded surfactants, ceramides and cholesterol-based lamellar phases as a topical treatment for psoriasis

research A rare case of multiple keratoacanthomas treated with oral acitretin and intralesional methotrexate

Community Join

community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

community Topical Finasteride and Minoxidil results after 1 year

community Topical min + topical fin + dermastamp weekly 1mm, about 9 weeks progress, i think it's going great so far

community Topical minoxidil can still kill cats even when the owner is “careful.”

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