learn Fluridil
a topical anti-androgen with less systemic involvement
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5 / 29 resultslearn Spironolactone
powerful topical and oral anti-androgen used mostly by women
learn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
learn Melatonin
hormone commonly taken for sleep aid has some topical benefits for hair
Research
5 / 1000+ results
research Comparison of Treatment with Clobetasol Propionate 0.05% and Topical Pimecrolimus 1% in Alopecia Areata
Clobetasol and pimecrolimus are similarly effective for alopecia areata, but pimecrolimus has fewer side effects and is preferred for long-term use.
research Resolution of Discoid Lupus Alopecia With Systemic Hydroxychloroquine and Topical Pimecrolimus Combination Therapy
Combining hydroxychloroquine and pimecrolimus can effectively treat hair loss from discoid lupus.
research Frontal Fibrosing Alopecia: Treatment with Oral Dutasteride and Topical Pimecrolimus
Oral dutasteride and topical pimecrolimus can safely and effectively treat Frontal Fibrosing Alopecia, leading to significant hair regrowth.
research Lack of Response of Alopecia Areata to Pimecrolimus Cream
Pimecrolimus cream is not effective for treating alopecia areata.
research A Case of Alopecia Areata Responding to Topical 1% Pimecrolimus Treatment
Topical 1% pimecrolimus effectively treated alopecia areata.
Community Join
5 / 1000+ resultscommunity I always hear the advice to reduce scalp inflammation. What are some non-steroidal ways to reduce inflammation?
Non-steroidal ways to reduce scalp inflammation include using topical melatonin, urea shampoo, Zyrtec, turmeric with black pepper, omega-3 supplements, a self-made topical solution with cetirizine, melatonin, and piroctone olamine, ketoconazole shampoo, witch hazel shampoo, tacrolimus, and lifestyle changes like a healthy diet and regular exercise. Some users also mentioned unconventional methods like infrared light therapy and a carnivore diet.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Why isn’t Topical Dutasteride the “Gold Standard”?
Topical dutasteride is more effective than finasteride for hair loss but lacks FDA approval and research, leading to less use. Users report varying effectiveness and side effects, with some preferring oral treatments.
community Phase II topical dut study - outperforms oral fin with a minor DHT reduction
Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.
community Topical Finasteride Pill filler
Users discuss making topical finasteride solutions by dissolving crushed tablets in ethanol and propylene glycol, with concerns about residue affecting effectiveness. They also mention using minoxidil and oral finasteride, noting some hair regrowth and no side effects from topical use.