109 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”
Targeting hair follicles can improve skin treatments and reduce side effects.
The conversation discusses positive initial trial results for GT20029, a topicalcompound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.
The conversation is about whether topical finasteride and minoxidil need to be applied directly to the affected areas of the scalp or if they can be spread through blood vessels. It also asks how long topical finasteride remains on a pillow.
Mixing RU58841 with minoxidil compounded with tretinoin is discussed, with concerns about systemic absorption. Topical dutasteride and finasteride are also mentioned as treatments, with varying personal experiences and concerns about side effects.
Using topical finasteride 0.1%, minoxidil 5%, and melatonin for 7 months reduced hair loss significantly, with increased libido and decreased stress tolerance. The user applies the solution once daily, uses nizoral twice weekly, and takes vitamin D and ZMA supplements.
People are discussing the use of topical melatonin for hair loss and how often it should be applied, with one person noting it makes them groggy in the morning. They are inquiring about others' application frequency.