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research Touch Receptors Undergo Rapid Remodeling in Healthy Skin

31 citations , November 2016 in “Cell Reports”

Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.

research Diversification and Specialization of Touch Receptors in Skin

81 citations , June 2014 in “Cold Spring Harbor perspectives in medicine”

Skin has specialized touch receptors that can tell different sensations apart.

research The Functional Diversity of Mammalian Touch Receptors

January 2016 in “Columbia Academic Commons (Columbia University)”

Mammalian touch receptors have evolved to detect different features, enhancing our ability to perform various tasks and interact socially.

Joint Public Review: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research Joint Public Review: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2

February 2024

Meis2 is essential for touch sensation and nerve function in mice.

ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2

February 2024

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

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community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 2 years ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community A concern regarding the upcoming androgen degrader drug GT20029

in Chat 10 upvotes 1 year ago

GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

community Does anyone have the removed Breezula phase II 12 month baseline comparison results?

in Research/Science 9 upvotes 5 years ago

The conversation discusses the removal of Breezula phase II 12-month results by Cassiopea and the search for the original data. Concerns were raised about potential negative long-term effects on hair growth, such as androgen receptor upregulation.

community Sugar and hairloss

in Research/Science 11 upvotes 5 years ago

Cutting sugar may not significantly impact hair loss, as DHT and androgen receptors are the main issues. Effective treatments include finasteride, dutasteride, RU58841, and minoxidil, often combined with microneedling.