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Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

The BUZZ gene is important for root hair growth and overall root structure in the plant Brachypodium distachyon.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Screening for the NUDT15 gene variant can prevent severe side effects from thiopurine drugs in East-Asian people.