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research An infant with congenital micrognathia and upper airway obstruction was diagnosed as Hutchinson-Gilford progeria syndrome caused by a novel LMNA mutation: Case report and literature review

1 citations , October 2023 in “Heliyon”

An infant with Hutchinson-Gilford Progeria Syndrome had successful surgery to fix breathing issues caused by a new genetic mutation.

research Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA

250 citations , November 2003 in “The Journal of Cell Biology”

BMP receptor IA is essential for proper hair cell differentiation in mice.

research CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata

64 citations , July 2016 in “Journal of Immunology”

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

research 264 CCR5 blockade shows prevention of alopecia areata development as well as improvement of alopecia areata

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Blocking CCR5 can prevent and improve hair loss in alopecia areata.

The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function

research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function

72 citations , January 2003 in “American Journal of Pathology”

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

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community Testosterone in Reference Range Doesn't Cause Hair Loss

in Research/Science 51 upvotes 2 years ago

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 39 upvotes 3 years ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community I have transcriptions of some of HairCafe's Dutasteride videos

in Finasteride/Dutasteride 14 upvotes 1 year ago

The conversation discusses the use of dutasteride and finasteride for hair loss, including switching between them, optimal dosing, and managing side effects. The user has transcriptions of videos on these topics and offers them to others interested.

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Hair Transplant Surgeon
Dr. Pulkit Chaturvedi
Indore, Madhya Pradesh, India

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Dr. Pulkit Chaturvedi