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research Study of Seed Hair Growth in Populus Tomentosa, an Important Character of Female Floral Bud Development

20 citations , June 2014 in “BMC genomics”

Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

research Complex Cellular Flows Shape Feather Follicle Topology

July 2024 in “Journal of Investigative Dermatology”

Cell movements and forces shape feather growth in chicken skin.

research Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome

34 citations , July 2020 in “American journal of human genetics”

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

Single-Cell RNA Sequencing of Different Fibroblast Populations Cultured from Female Scalp Reveals Significant Alterations to Transcriptional Profiles with Age

research Single-Cell RNA Sequencing of Different Fibroblast Populations Cultured from Female Scalp Reveals Significant Alterations to Transcriptional Profiles with Age

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Aging changes female scalp cells, likely affecting hair health.

research The Transcriptional Landscape of Seasonal Coat Color Moult in the Snowshoe Hare

28 citations , May 2017 in “Molecular ecology”

Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.

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community Testosterone in Reference Range Doesn't Cause Hair Loss

in Research/Science 49 upvotes 2 years ago

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

community 50% test increase after 18 months of taking DUT

in Update 57 upvotes 1 year ago

A user reported a 50% increase in testosterone after 18 months of taking dutasteride for hair loss. The conversation includes skepticism about the reliability of single testosterone tests and questions about estrogen levels.

community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)

nkrata in Research 461 upvotes 9 months ago

Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.

community Minoxidil is a 5ar inhibitor according to research

in Research/Science 146 upvotes 5 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community DHT/Testosterone levels in scalp Fin VS Dut.

in Finasteride/Dutasteride 66 upvotes 1 year ago

Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

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