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Research

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research Type 1 interferon signature in the scalp lesions of alopecia areata

52 citations , March 2010 in “British Journal of Dermatology”

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

research Type 1 interferon signature and cytotoxic T lymphocyte activation targeted against sweat ducts in inflammatory acquired idiopathic generalized anhidrosis

6 citations , June 2023 in “Journal of the European Academy of Dermatology and Venereology”

Inflammation damages sweat ducts, causing sweat gland injury.

research The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

71 citations , May 2024 in “New England Journal of Medicine”

Ruxolitinib may effectively treat APS-1 by reducing harmful immune responses.

Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis

research 1326 Translation-dependent skin hyperplasia is promoted by type 1/17 inflammation in psoriasis

April 2023 in “Journal of Investigative Dermatology”

Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.

research Autoimmune Polyglandular Syndrome Type 1 in Russian Patients: Clinical Variants and Autoimmune Regulator Mutations

62 citations , January 2010 in “Hormone research in paediatrics”

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

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Community Join

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community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

in Finasteride/Dutasteride 30 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community 10 month update - 4 in 1 topical solution + dermastamp (sorry for the low quality before)

in Progress Pictures 307 upvotes 4 months ago

A user shared their positive experience with a 4-in-1 topical solution containing finasteride, minoxidil, ketoconazole, and biotin, along with weekly microneedling using a 1.2mm dermastamp. The user reported no noticeable side effects and mentioned that the biotin likely doesn't contribute to hair growth.

community 3 years of 1 mg of Finasteride daily

in Progress Pictures 867 upvotes 5 years ago

A user who was able to regrow hair loss with 1mg of finasteride daily over 3 years, the effectiveness of finasteride for different races, and potential side effects associated with taking finasteride.

community 3 months on the big 4 (liposomal gel min fin, keto shampoo and microneedling 1.5mm weekly) let me know what you think

in Progress Pictures 83 upvotes 3 years ago

A user's progress after 3 months of using the "big 4" hair loss treatments - liposomal gel minoxidil, finasteride, keto shampoo and microneedling; with people providing advice about their own experiences and asking for more information.

community New vellus all over — just 9 days into once-daily 5% minoxidil.

in Minoxidil 159 upvotes 7 months ago

The user has been using 1 mg finasteride for three months and recently started using 5% minoxidil once daily, resulting in new vellus hair growth. The user is hopeful that minoxidil will positively impact terminal hairs and is considering adding a derma stamp to the routine.

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Learn

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learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

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Experts

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Clinics

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