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Tracking 1 products like 132 URODART 0.5MG 28 capsule from by companies like Minoxidil Express. View product »

Research

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Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase Predominates in Human Sebaceous Glands

research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands

45 citations , September 1998 in “Journal of Investigative Dermatology”

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

research Determination of rat 5α-reductase type 1 isozyme activity and its inhibition by novel steroidal oxazolines

4 citations , August 2010 in “Acta Biologica Hungarica”

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.

53 citations , June 1993 in “Proceedings of the National Academy of Sciences of the United States of America”

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

research Immunolocalization of 5α-Reductase Isozymes in Acne Lesions and Normal Skin

45 citations , September 2000 in “Archives of dermatology”

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

research Die pathogenetische Bedeutung der 5α-Reduktase-Isoenzyme für die androgenetische Alopezie

9 citations , March 1999 in “Der Hautarzt”

Type 2 5α-reductase plays a key role in hair loss.

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community Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate.

in Research/Science 9 upvotes 3 years ago

Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.

community 20M, 2 years of minoxidil + microneedling… Still losing hair. Need advice on finasteride sources

in General 184 upvotes 11 months ago

A 20-year-old has been using minoxidil and microneedling for hair loss but is still losing hair and is considering finasteride or dutasteride for more effective treatment. They seek advice on reliable online sources for purchasing finasteride in Italy.

community 22M loosing ground - 1MG fin + 2% Keto Shampoo

in Is this regrowth? 40 upvotes 2 years ago

A 22-year-old using finasteride and 2% ketoconazole shampoo for hair loss sees mixed results after three months, with some improvement at the crown but worsening at the temples. Suggestions include waiting 6-12 months, considering dutasteride, adding minoxidil, microneedling, caffeine tonic, and retinol.

community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.

in Finasteride/Dutasteride 52 upvotes 3 years ago

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

community 4 months of topical minoxidil with derma rolling starting at month 2 - my review / experience

in Is this regrowth? 45 upvotes 1 year ago

The user has been using topical minoxidil and dermarolling for hair regrowth but is hesitant to start finasteride due to potential side effects. Many suggest adding finasteride for better results in addressing DHT-related hair loss.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

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