research High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.
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5 / 1000+ results research Presence of a Deletion Mutation (c.716delA) in the Ligand Binding Domain of the Vitamin D Receptor in an Indian Patient with Vitamin D-Dependent Rickets Type II
A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.
research Increased Androgen Binding Capacity in Sebaceous Glands in Scalp of Male-pattern Baldness
Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.
research Androgen Regulation of the Human Hair Follicle: The Type I Hair Keratin hHa7 Is a Direct Target Gene in Trichocytes
The hHa7 gene is regulated by androgens in certain body hair, not scalp hair.
research Sex hormone–binding globulin and risk of hyperglycemia in patients with androgenetic alopecia
People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.
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5 / 1000+ resultscommunity Pyrilutamide binding affinity is similar to RU
Comparing the effectiveness of RU58841, Pyrilutamide and CB-03-01 as treatments for hair loss, with people discussing different aspects such as binding affinity, time of inhibition, safety data and cost.
community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?
Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.
community The insanity of hair loss is blinding
The conversation revolves around the psychological impact of hair loss and various treatments. Participants discuss using Minoxidil (Min) and Finasteride (Fin), hair transplants, and therapy for mental health. Some also recommend immediate action at the first signs of hair loss and joining supportive communities.
community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.
Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.
community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.
Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.
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3 / 801 resultslearn Stem Cell Factor
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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Experts
6 / 22 results- 36Hair System Specialist
Tye Brock Meredith
Redding, CA, United States
- 28
SMP SpecialistKelsey Tyre
Wilmington, DE, United States
- 5
Hair System SpecialistDebbie, 15+ years specialising in hair toppers and alternative hair solutions, Extensive training with Wavy, Curly, and Afro hair
Incomplete name
East Toowoomba, QLD, Australia
- UnscoredHair System Specialist
dipu
Incomplete name
Uluberiya, India
- 12Hair Transplant Surgeon
Dr. Deepa, MD, MBBS
Incomplete name
Coimbatore, Tamil Nadu, India
- 1Hair System Specialist
Debbie
Incomplete name
United Kingdom
Clinics
6 / 10 results- 34
Hair Loss TreatmentsTye & Company Salon & Hair Loss StudioBaltimore, MD · US - 15Hair Loss TreatmentsScalp paintingSeoul · KR
- 27Hair SystemsHAIR FIXING BONDING WEAVING CENTERGyānpur, Uttar Pradesh · IN
- 30Hair Loss TreatmentsKlinik Kecantikan Bandung Skin CentreBandung · ID
- 19Hair SystemsHair Patch and Bonding ServiceAgra, Uttar Pradesh · IN
- 31Hair TransplantBeautylogica Clinic - BandungBandung · ID